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Aspirin inhibits the negative feedback loop that would reduce ß-agonist production. So taken together these virtual fitness trainer agents enhance three to four different steps in the ß-agonist pathway. Ephedrine's role as a lipolytic agent (one that breaks down body fat to be used as energy) has virtual fitness trainer been known for some time. It has been shown that ephedrine when taken in therapeutic doses is mildly effective in the management of obesity. The problem was that the initial lipolytic effects of ephedrine were soon virtual fitness trainer diminished as other steps in the pathway were reduced in a negative feedback cycle. In an effort to enhance these steps that were being downregulated due to negative feedback, scientists added caffeine and aspirin to the regime. The result was a very effective combination in the management of obesity (dosages given were 20mg ephedrine, 300mg caffeine, and 80mg aspirin, roughly equivalent to one typical ephedrine tablet, a cup of coffee and one aspirin).
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